Benefits of coenzyme Q10 for dogs: scientific evidence

Healthy dog

Today the benefits of coenzyme Q10 for the treatment of canine diseases are recognized. It is essential to know that coenzymes are a type of biological substance that exists in the body of our dogs, and also in ours.

In the case of Q10, it is known that it is highly abundant during childhood and youth and that it declines in old age. Hence many supplements try to replace this component.

At present, a cluster of scientific evidence confirms the benefits of coenzyme Q10. These studies have corroborated its value as a nutritional supplement for the treatment of various diseases. In this article, you will find out what’s new in the use of this supplement.

What is coenzyme Q10?

Coenzyme Q10 (CoQ10), also known as ubiquinone, is an endogenous, lipid-soluble compound that exists in all human and animal cells.

This is a substance similar to vitamins; it is found throughout the body in humans and animals. It is especially abundant in the heart, liver, kidneys, and pancreas.

Thus, this substance is naturally produced by your dog, but it can also be obtained from the diet. Foods that contain high concentrations of CoQ10 include fatty fish (salmon, mackerel, sardines), viscera, and whole grains.

Coenzyme Q10 is most often used for heart conditions, such as heart failure and fluid accumulation in the body (congestive heart failure or CHF).

How does coenzyme Q10 work?

CoQ10 is a powerful antioxidant and reduces damage to cells caused by free radicals (these are molecules that have been changed by oxidation and cause damage to cells).

An essential function of CoQ10 is that it constitutes a link in the body’s energy production process.

For this reason, those organs with the highest energy requirements, such as the liver, heart, and kidneys, have the highest amounts of CoQ10.

CoQ10 deficiency in dogs

Two main factors can lead to a lack of CoQ10: that the body produces less CoQ10 or that there is greater use by the body.

Endogenous synthesis is the primary source of CoQ10. Old age and several diseases, including some that are inherited, can cause deficiency of this coenzyme.

Benefits of coenzyme Q10 in the treatment of canine diseases

Cardiovascular disease

CoQ10 levels are reduced in the hearts of pets with heart disease. Accordingly, the most frequent use of CoQ10 in dogs is an adjunct in the treatment of congestive heart failure.

Coenzyme Q10 is useful in the treatment of canine cardiomyopathy and related diseases.

Periodontal disease

Among the benefits of coenzyme Q10 is that it can help in the treatment of periodontal disease or gums.

CoQ10 supplementation has been shown to reduce the size and improve the health of periodontal pockets. It does so by decreasing inflammation, redness, bleeding, and pain.

Because most pets with heart disease also have periodontal disease, supplementation with CoQ10 may offer an additional benefit by being effective in both conditions.

Canine cognitive dysfunction syndrome (DCC)

Canine cognitive dysfunction syndrome (DCC) is a neurodegenerative disease related to aging. There is a marked similarity between DCC and Alzheimer’s disease in humans.

Scientific studies reveal that the best treatment option is to combine pharmacological and nutritional therapy. As a nutraceutical, the incorporation of CoQ10 into CCD treatment has been tremendously successful.


CoQ10 can help prevent heart damage caused by certain types of cancer chemotherapy, such as adriamycin.

Keep in mind that because the antioxidant activity of CoQ10 could interfere with the action of other chemotherapy drugs. For this reason, consult your veterinarian before using CoQ10 if your dog has cancer that requires chemotherapy.

CoQ10 can also increase the effectiveness of other antioxidants, such as vitamin C, and help with immune problems, diabetes, and reduced physical performance.

How safe is coenzyme Q10?

As a supplement, CoQ10 coenzyme appears to be extremely safe. And it should be noted that no significant side effects have been found.

However, veterinary supervision is recommended to ensure that pets with severe heart disease are improving and that any decrease in function is addressed.

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